Apparent Mutations Observed at STR Loci in the Course of Paternity Testing*

STR System

Maternal Meioses (%)

Paternal Meioses

(%)

Number from either

Total Number of Mutations

Mutation Rate

CSF1PO

95/304,307 (0.03)

982/643,118 (0.15)

410

1,487/947,425

0.16%

FGA

205/408,230 (0.05)

2,210/692,776 (0.32)

710

3,125/1,101,006

0.28%

TH01

31/327,172 (0.009)

41/452,382 (0.009)

28

100/779,554

0.01%

TPOX

18/400,061 (0.004)

54/457,420 (0.012)

28

100/857,481

0.01%

VWA

184/564,398 (0.03)

1,482/873,547 (0.17)

814

2,480/1,437,945

0.17%

D3S1358

60/405,452 (0.015)

713/558,836 (0.13)

379

1,152/964,288

0.12%

D5S818

111/451,736 (0.025)

763/655,603 (0.12)

385

1,259/1,107,339

0.11%

D7S820

59/440,562 (0.013)

745/644,743 (0.12)

285

1,089/1,085,305

0.10%

D8S1179

96/409,869 (0.02)

779/489,968 (0.16)

364

1,239/899,837

0.14%

D13S317

192/482,136 (0.04)

881/621,146 (0.14)

485

1,558/1,103,282

0.14%

D16S539

129/467,774 (0.03)

540/494,465 (0.11)

372

1,041/962,239

0.11%

D18S51

186/296,244 (0.06)

1,094/494,098 (0.22)

466

1,746/790,342

0.22%

D21S11

464/435,388 (0.11)

772/526,708 (0.15)

580

1,816/962,096

0.19%

Penta D

12/18,701 (0.06)

21/22,501 (0.09)

24

57/41,202

0.14%

Penta E

29/44,311 (0.065)

75/55,719 (0.135)

59

163/100,030

0.16%

D2S1338

15/72,830 (0.021)

157/152,310 (0.10)

90

262/225,140

0.12%

D19S433

38/70,001 (0.05)

78/103,489 (0.075)

71

187/173,490

0.11%

SE33 (ACTBP2)

0/330 (<0.30)

330/51,610 (0.64)

None reported

330/51,940

0.64%

*Data used with permission from American Association of Blood Banks (AABB) 2003 Annual Report.

 

Includes compilation of multiple years. Information also available on population and allele-specific mutation rates  (see http://www.aabb.org/sa/facilities/Pages/relationshipreports.aspx).

A total of 44 different paternity testing laboratories provided this STR mutation data.

 

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