New York DNA Training Workshop

Topics and Techniques for Forensic DNA Analysis

Continuing Education Seminar


 Full-day workshop at NYC Office of Chief Medical Examiner Forensic Biology (Manhattan, NY)

Wednesday, April 18, 2012


John M. Butler, Ph.D. & Michael D. Coble, Ph.D.

National Institute of Standards and Technology

To view or print slide handouts (6-slides to a page), click on highlighted topics in the agenda.




9:00 – 9:20 a.m. Introductions


9:20 – 10:30 a.m. Data Interpretation & Statistical Analysis Overview


10:30 – 10:45 a.m. BREAK


10:45 a.m. – 12:15 p.m. Mixture Interpretation


12:15 – 1:30 p.m. LUNCH


1:30 – 3:00 p.m. STR Markers and CE Instrumentation


3:00 – 3:15 p.m. BREAK


3:15 – 4:45 p.m. Y-STRs, mtDNA, and the Romanov Case


4:45 – 5:00 p.m. Q&A


For full-page slides: [Introductions] [Data Interpretation & Stats Overview] [Mixture Interpretation] [STRs & CE] [Y, mtDNA, Romanovs]


Recommended further reading list

Rudin, N. and Inman, K. (2012) The discomfort of thought - a discussion with John Butler. The CAC News, 1st Quarter 2012, pp. 8-11. Available at

Butler, J.M. and Hill, C.R. (2012) Biology and genetics of new autosomal STR loci useful for forensic DNA analysis. Forensic Sci. Rev. 24(1): 15-26.

Buckleton, J.S. and Curran, J.M. (2008) A discussion of the merits of random man not excluded and likelihood ratios. Forensic Sci. Int. Genet. 2: 343-348.

Budowle, B., et al. (2009) Mixture interpretation: defining the relevant features for guidelines for the assessment of mixed DNA profiles in forensic casework. J. Forensic Sci. 54: 810-821.

Clayton, T.M., et al. (1998) Analysis and interpretation of mixed forensic stains using DNA STR profiling. Forensic Sci. Int. 91: 55-70.

Gill, P., et al. (2006) DNA commission of the International Society of Forensic Genetics: Recommendations on the interpretation of mixtures. Forensic Sci. Int. 160: 90-101.

Gill, P., et al. (2008) National recommendations of the technical UK DNA working group on mixture interpretation for the NDNAD and for court going purposes. FSI Genetics 2(1): 76–82.

Schneider, P.M., et al. (2009) The German Stain Commission: recommendations for the interpretation of mixed stains. Int. J. Legal Med. 123: 1-5.

Coble, M.D., Loreille, O.M., Wadhams, M.J., Edson, S.M., Maynard, K., Meyer, C.E., Niederstätter, H., Berger, C., Berger, B., Falsetti, A.B., Gill, P., Parson, W., Finelli L.N. (2009) Mystery solved: the identification of the two missing Romanov children using DNA analysis. PLoS ONE 4(3): e4838.


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Revised: 04/17/2012